Per 1000 catheter-days), as well as of overall thrombotic complications (21.5% catheter-days) and of major infectiousĬomplications (clinical sepsis with or without bloodstream infection, 4.4% Of overall infectious complications (19.8% vs 4.5% P<.001 Results Femoral catheterization was associated with a higher incidence rate Main Outcome Measures Rate and severity of mechanical, infectious, and thrombotic complications,Ĭompared by catheterization site in 289, 270, and 223 patients, respectively. Interventions Patients were randomly assigned to undergo central venous catheterizationĪt the femoral site (n = 145) or subclavian site (n = 144). Patients Two hundred eighty-nine adult patients receiving a first central venous Objective To compare mechanical, infectious, and thrombotic complications of femoralĭesign and Setting Concealed, randomized controlled clinical trial conducted between Decemberġ997 and July 2000 at 8 intensive care units (ICUs) in France. Shared Decision Making and CommunicationĪuthor Affiliations: Service de Réanimation Médicale (Drs Merrer, De Jonghe, and Outin) and Service de Réanimation Chirurgicale (Dr Raffy), Centre Hospitalier de Poissy/St Germain-en-Laye, Poissy, France Centre de Coordination et de Lutte Contre les Infections Nosocomiales de Paris-Nord (Mr Golliot) and Service de Réanimation Polyvalente, Hôpital Saint Joseph (Dr Misset), Paris, France Département d'Urgence Réanimation, Centre Hospitalo-Universitaire de Nîmes, Nîmes, France (Dr Lefrant) Service de Réanimation Polyvalente, Centre Hospitalier de Mantes-la-Jolie, Mantes-la-Jolie, France (Dr Barre) Service de Réanimation Médicale, Centre Hospitalier de Dieppe, Dieppe, France (Dr Rigaud) Service de Réanimation Polyvalente, Centre Hospitalier de Villeneuve-Saint-Georges, Villeneuve-Saint-Georges, France (Dr Casciani) Service de Réanimation Médicale, Centre Hospitalo-Universitaire de Strasbourg, Strasbourg, France (Dr Bosquet) Service de Réanimation Médicale, Centre Hospitalo-Universitaire Henri Mondor, Creteil, France (Dr Brun-Buisson) and Service de Réanimation Medico-Chirurgicale, Institut Gustave-Roussy, Villejuif, France (Dr Nitenberg).Ĭontext Whether venous catheterization at the femoral site is associated withĪn increased risk of complications compared with that at the subclavian site.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience. Challenges in Clinical Electrocardiography.
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